Shaaha madow, oo si buuxda u khamiirsan, ayaa ah shaaha ugu isticmaalka badan adduunka. Marka la farsamaynayo, waa in la maro engegan, rogrogasho iyo halsano, taas oo sababta falcelinta biochemical ee kakan ee maaddooyinka ku jira caleenta shaaha oo aakhirka dhalata dhadhankeeda gaarka ah iyo saamaynta caafimaad ee ay leedahay. Dhawaan, kooxda cilmi-baarista ee uu hoggaamiyo Prof. WANG Yuefei oo ka socda kulliyadda beeraha iyo cilmiga bayoolajiga, Jaamacadda Zhejiang, waxay sameeyeen horumar isdabajoog ah oo ku saabsan samaynta tayada iyo shaqada caafimaadka ee shaaha madow.

Iyadoo la adeegsanayo qiimeynta dareenka iyo dheef-shiid kiimikaadka si loo falanqeeyo saameynta cabbirrada kala duwan ee wax-soo-saarka ee shaaha madow ee Zijuan, kooxdu waxay ogaatay in phenylacetic acid iyo glutamine ay si weyn ugu xiran yihiin udgoonka iyo dhadhanka shaaha madow ee Zijuan, siday u kala horreeyaan, sidaas darteed bixinta tixraaca hagaajinta farsamada farsamaynta ee shaaha madow ee Zijuan (Zhao et al., LWT -Sayniska Cunnada iyo Tignoolajiyada, 2020). Daraasadihii xigay, waxay ogaadeen in uruurinta oksijiinta ay kor u qaadi karto catechins, flavonoid glycosides iyo phenolic acids, iyo oxidation catekins waxay dardar gelin kartaa hoos u dhaca acids amino si ay u sameeyaan aldehydes kacsan waxayna kor u qaadaan oksida acids phenolic, taas oo hoos u dhigaysa astringency iyo qadhaadhka iyo xoojinta umami , kaas oo siinaya aragti cusub oo ku saabsan samaynta u qalmida shaaha madow. Natiijooyinkan cilmi-baarista ayaa lagu daabacay maqaal cinwaan looga dhigay " Halsano Ogsajiin-ku-kordhinta waxay wanaajisaa dhadhanka shaaha madow iyadoo yareyneysa dheef-shiid kiimikaadka qadhaadh iyo astringent" ee joornaalka.International Research Researchbisha Luulyo, 2021.

Isbeddellada dheef-shiid kiimikaadka aan isbeddelayn inta lagu jiro farsamaynta waxay saameeyaan tayada iyo shaqada caafimaad ee suurtagalka ah ee shaaha madow. Bishii Noofambar 2021, kooxdu waxay daabacday maqaal gelitaan furan oo ciwaankiisu yahay "Isbeddellada dheef-shiid kiimikaadka aan isbeddelayn inta lagu jiro ka-hortagga shaaha madow ee Zijuan waxay saameeyaan awoodda ilaalinta HOEC-yada nikotiinka"Cuntada & Shaqada. Daraasadani waxay muujisay in leucine, isoleucine, iyo tyrosine ay yihiin wax soo saarka hydrolysis ee ugu muhiimsan inta lagu jiro engegan, iyo theaflavin-3-gallate (TF-3-G), theaflavin-3'-gallate (TF-3'-G) iyo theaflavin-3 ,3'-gallate (TFDG) ayaa inta badan la sameeyay xilliga duubista. Waxaa intaa dheer, oksaydheynta flavonoid glycosides, catechins iyo catechin dimeric ayaa dhacay intii lagu jiray halsano. Inta lagu jiro qalajinta, beddelka amino acid ayaa noqday mid awood badan. Isbeddellada theaflavins, qaar ka mid ah acids amino iyo flavonoid glycosides ayaa saameyn weyn ku yeeshay iska caabinta shaaha madow ee Zijuan si ay nikotiintu u keento dhaawaca unugyada epithelial ee bini'aadamka, taas oo muujinaysa in kobcinta maaddooyinka firfircoon ee gaarka ah iyo xoojinta hawlaha gaarka ah ee shaaha madow habka wax soo saarka ee shaaha madow waxay noqon kartaa fikrad xariif ah oo ku saabsan habka wax soo saarka shaaha.

Bishii Disembar 2021, kooxdu waxay daabacday maqaal kale oo cinwaankeedu yahay "Shaaha Madow wuxuu yareeyaa dhaawaca sambabada ee qayb ka mid ah maadada sambabada iyada oo loo sii marayo dhidibka mindhicirka-sanbabada ee jiirarka" gudahaWargeyskaKiimikada Beeraha iyo Cuntada. Daraasadani waxay muujisay in PM (material particulate) -jiirarka soo bandhigay ay muujiyeen cadaadiska oksaydhka iyo bararka sanbabada, taas oo si weyn loo yareyn karo qaadashada maalinlaha ah ee faleebo shaaha madow ee Zijuan qaab ku tiirsan. Waxa xiiso leh, labadaba jajabka ethanol-soluble (ES) iyo jajabka ethanol-ka-soo-saarka (EP) labaduba waxay muujiyeen saameyn ka wanaagsan kuwa TI. Intaa waxaa dheer, ku-tallaalidda saxarada mikrobiota (FMT) ayaa shaaca ka qaaday in microbiota mindhicirka ay si kala duwan u qaabeeyeen TI iyo jajabkeedu waxay awoodeen inay si toos ah u yareeyaan dhaawaca ay keeneen PMs. Intaa waxaa dheer,Kooxda Lachnospiraceae_NK4A136waxay noqon kartaa microbe-ka xudunta u ah mindhicirka ee ka qayb qaadanaya ilaalinta EP. "Natiijooyinkani waxay muujiyeen in qaadashada maalinlaha ah ee shaaha madow iyo jajabkeeda, gaar ahaan EP, laga yaabo inay yareeyaan dhaawacyada sambabada ee PM-ku-soo-baxa iyada oo loo marayo dhidibka sanbabada ee jiirarka, sidaas darteed bixinta tixraacyo aragti ah oo ku saabsan shaqada caafimaadka ee shaaha madow," ayuu yiri Wang.